• Am J Med Qual · Jan 2015

    Review Meta Analysis

    Outcome of adverse events and medical errors in the intensive care unit: a systematic review and meta-analysis.

    • Adil H Ahmed, Jyothsna Giri, Rahul Kashyap, Balwinder Singh, Yue Dong, Oguz Kilickaya, Patricia J Erwin, M Hassan Murad, and Brian W Pickering.
    • Mayo Clinic, Rochester, MN ahmed.adil@mayo.edu.
    • Am J Med Qual. 2015 Jan 1; 30 (1): 23-30.

    AbstractAdverse events and medical errors (AEs/MEs) are more likely to occur in the intensive care unit (ICU). Information about the incidence and outcomes of such events is conflicting. A systematic review and meta-analysis were conducted to examine the effects of MEs/AEs on mortality and hospital and ICU lengths of stay among ICU patients. Potentially eligible studies were identified from 4 major databases. Of 902 studies screened, 12 met the inclusion criteria, 10 of which are included in the quantitative analysis. Patients with 1 or more MEs/AEs (vs no MEs/AEs) had a nonsignificant increase in mortality (odds ratio = 1.5; 95% confidence interval [CI] = 0.98-2.14) but significantly longer hospital and ICU stays; the mean difference (95% CI) was 8.9 (3.3-14.7) days for hospital stay and 6.8 (0.2-13.4) days for ICU. The ICU environment is associated with a substantial incidence of MEs/AEs, and patients with MEs/AEs have worse outcomes than those with no MEs/AEs. © 2013 by the American College of Medical Quality.

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