• Shuang Wang, Yajie Gong, Keke Huang, and Jun Huang.
• Ophthalmology Department, Chengdu Third People's Hospital, Southwest Jiaotong University, Chengdu, Sichuan, China.
• Medicine (Baltimore). 2024 Aug 30; 103 (35): e39482e39482.

RationaleCompared with intraocular tuberculosis, ocular tuberculosis with ocular surface involvement is rare. Corneal involvement in ocular tuberculosis may include interstitial keratitis or peripheral ulcerative keratitis. We report a case of peripheral ulcerative keratitis directly caused by tuberculosis.Patient ConcernsA 20-year-old man complained of vision loss and pain in the left eye that had lasted for 1 week. A slit lamp examination of the left eye showed a corneal epithelial defect, interstitial corneal edema, and a white irregular infiltrative lesion and ulcer (with the dimension of 2 × 2.5 mm) in the inferior temporal region.DiagnosesThe corneal ulcer was scraped, and the Mycobacterium tuberculosis deoxyribonucleic acid polymerase chain reaction was positive.Interventions And OutcomesAfter a month of oral antituberculosis treatment, the corneal ulcer resolved, and the intraocular inflammation improved.LessonsPeripheral ulcerative keratitis secondary to tuberculosis can be directly caused by M tuberculosis.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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