• Bo Wang, Hui Shi, Yuntai Yao, Shen Liu, and Chunxia Shi.
• Department of Anesthesiology, Peking University International Hospital, Beijing, China.
• J. Cardiothorac. Vasc. Anesth. 2024 Nov 1; 38 (11): 260626122606-2612.

ObjectivesThe objective of this systematic review was to clarify the status of near-infrared spectroscopy (NIRS) in monitoring perioperative renal regional tissue oxygen saturation (rSO2) and determine whether there is evidence supporting its use in predicting postoperative acute kidney injury (AKI).DesignA systematic search of electronic databases was conducted to identify all clinical studies that utilized NIRS to monitor renal rSO2 during the perioperative period to observe postoperative AKI.SettingStudies published online as of May 31, 2024, were included in the review.ParticipantsStudies involving human participants undergoing surgery with a predefined outcome of AKI were included.InterventionsRegional tissue oxygen saturation was measured using NIRS.Measurements And Main ResultsA total of 144 records were identified in the primary search after removing duplicates. After screening, 18 studies were included in the analysis, consisting of 3 case-control studies and 15 prospective cohort studies. Thirteen reports focused on pediatric surgery, whereas five reports focused on adult surgery. Sixteen studies involved cardiovascular surgery with cardiopulmonary bypass, and two studies focused on liver surgery. All studies received a quality score of 7 or above. Significant heterogeneity and mostly short follow up periods were noted.ConclusionRenal desaturation may indicate AKI in patients; however, further studies are required to substantiate this relationship. Additional clinical trials are necessary to evaluate normal values and establish the exact threshold of renal rSO2 that signifies a meaningful decline in renal function.Copyright © 2024. Published by Elsevier Inc.

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