• Internal medicine · Sep 2024

    Zoster Sine Herpete Affecting Multiple Lower Cranial Nerves Presenting Severe Dysphagia in a Patient with Parkinson's Disease.

    • Akira Yokote, YamashitaKen-IchiroKIDepartment of Neurology, Brain and Nerve Center, Fukuoka Central Hospital, Japan.Translational Neuroscience Research Center, Graduate School of Medicine, International University of Health and Welfare, Japan., Ayako Sakoda, Yasutaka Iwanaga, Yuri Nakamura, Keiko Haro, Yasuhiro Kanamoto, Naoko Matsubara, and Jun-Ichi Kira.
    • Department of Neurology, Brain and Nerve Center, Fukuoka Central Hospital, Japan.
    • Intern. Med. 2024 Sep 4.

    AbstractWe report the case of a 74-year-old woman with Parkinson's disease (PD) who developed acute dysphagia, dysarthria, and hoarseness. A neurological examination and nasopharyngeal fiberscopy revealed paralysis of the left glossopharyngeal, vagus, and hypoglossal nerves. No skin rash was observed. Cerebrospinal fluid testing showed lymphocytic pleocytosis, and an elevated varicella-zoster virus (VZV) IgG antibody index. She was diagnosed with zoster sine herpete unilaterally affecting multiple lower cranial nerves. Although dysphagia is common in patients with PD, acute exacerbations of dysphagia require careful investigation of various potential causes, including VZV infection.

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