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- Nobuhiko Ohashi, Yoshino Kawamura, Shota Kamijima, Rie Watanabe, Shintaro Yamazaki, Nodoka Matsushima, and TazawaKo-IchiKIDepartment of Neurology, Nagano Red Cross Hospital, Japan..
- Department of Neurology, Nagano Red Cross Hospital, Japan.
- Intern. Med. 2024 Sep 18.
AbstractWe herein report an 81-year-old woman with no significant medical history who developed a fever, headache, and right eyelid swelling. Magnetic resonance imaging (MRI) showed eye proptosis, sphenoid opacity, enlarged cavernous sinus, and dilated right superior ophthalmic vein (SOV). Subsequent enhanced MRI revealed intraventricular debris and thrombosis in the right SOV and the left transverse and sigmoid sinuses. Blood cultures were positive for Aggregatibacter aphrophilus, as identified by mass spectrometry. The patient responded well to antibiotics, anticoagulants, and surgical drainage of sphenoid sinusitis. To our knowledge, this is the first case of A. aphirophilus sphenoid sinusitis causing orbital cellulitis, meningitis, and venous sinus thrombosis.
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