• Internal medicine journal · Nov 2024

    Review

    Clinical perspectives: Takotsubo cardiomyopathy.

    • Jayant Ravindran and David Brieger.
    • Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
    • Intern Med J. 2024 Nov 1; 54 (11): 178517951785-1795.

    AbstractTakotsubo syndrome is a condition characterised by temporary acute left ventricular dysfunction with regional wall abnormalities extending beyond a single coronary artery territory. Initially thought to be benign, this condition, which is challenging to distinguish from acute coronary syndrome, has substantial morbidity and mortality. The mechanism behind this condition remains elusive, but multiple theories have been proposed. Although beta blockers and angiotensin-converting enzyme inhibitors are used as treatments for left ventricular dysfunction, currently, there are no randomised controlled trials to support their use. In this paper, we review the latest evidence regarding aetiologies, pathophysiology, diagnostic criteria, prognosis, complications and management of Takotsubo syndrome.© 2024 Royal Australasian College of Physicians.

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