• Annals of medicine · Dec 2024

    Review

    Delirium in the ICU: how much do we know? A narrative review.

    • Si Bo Liu, Hong Yu Wu, Mei Li Duan, Rong Li Yang, Chen Hua Ji, Jin Jie Liu, and Hongtao Zhao.
    • Intensive Care Unit, Dalian Municipal Central Hospital Affiliated Dalian University of Technology, Dalian, China.
    • Ann. Med. 2024 Dec 1; 56 (1): 24050722405072.

    AbstractDelirium in critical ill patients is a complex and common neurological syndrome in the intensive care unit (ICU) that is caused by a range of structural or functional abnormalities. ICU Delirium is associated with reduced compliance, prolonged hospital stays, greater use or delayed withdrawal of sedatives, higher rates and durations of mechanical ventilation, and higher rates of mortality. The aetiology and pathogenesis of ICU delirium are unclear, and the lack of better prediction, prevention, and treatment measures leads to a non-standardized control of delirium. By searching the relevant literature, we aim in this narrative review to describe progress in the pathogenesis, predictive biomarkers, diagnosis, and treatment of ICU delirium.

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