• Namita Ghimire, Santoshi Adhikari, Subhanshi Sharma, Rojina Basnet, Richa Acharya, Shashi Verma, and Pradip Gyanwali.
• Nepal Health Research Council, Ramshah Path, Kathmandu, Nepal.
• JNMA J Nepal Med Assoc. 2024 Feb 29; 62 (271): 174179174-179.

IntroductionThe universal health research ethical principles must be adhered to ensure a balance between science and safeguarding participants' rights, safety and dignity. A cross-sectional study was conducted to assess the knowledge, attitude, and practice of research ethics among researchers in Nepal.MethodsThe study was carried out among 449 researchers who submitted proposals for ethical review and approval from the Ethical Review Board of the Nepal Health Research Council between January 2017 to August 2021. Simple random sampling was done ensuring a proportional representation of researchers from all areas of health research. A structured questionnaire was administered online for data collection.ResultsThe participants aged between 23-80 years old consented to complete the survey questionnaire. The median age of the respondents was 35 (23-80) years. Among all the respondents, 52 (11.58%) were unaware about the National Ethical Guideline for Health Research. Similarly, 110 (24.50%) respondents strongly agreed that the ethical review process impairs research and makes it harder for researchers to conduct research; 372 (82.85%) respondents had pursued research activity only after obtaining ethical approval.ConclusionsHalf of the respondents had knowledge on different aspects of research ethics.

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