• Roy M Gulick, Alice K Pau, Eric Daar, Laura Evans, Rajesh T Gandhi, Pablo Tebas, Renée Ridzon, Henry Masur, H Clifford Lane, NIH COVID-19 Treatment Guidelines Panel, Adaora A Adimora, Jason Baker, Lisa Baumann Kreuziger, Roger Bedimo, Pamela Belperio, Anoopindar Bhalla, Timothy Burgess, Danielle Campbell, Stephen Cantrill, Kara Chew, Kathleen Chiotos, Craig Coopersmith, Richard Davey, Amy Dzierba, Derek Eisnor, Gregory Eschenauer, Joseph Francis, John Gallagher, David Glidden, Neil Goldenberg, Birgit Grund, Alison Han, Erica Hardy, Carly Harrison, Lauren Henderson, Elizabeth Higgs, Carl Hinkson, Brenna Hughes, Steven Johnson, Marla Keller, Arthur Kim, Richard Knight, Safia Kuriakose, Jeffrey Lennox, Andrea Lerner, Mitchell Levy, Jonathan Li, Christine MacBrayne, Greg Martin, Nandita Nadig, Martha Nason, Pragna Patel, Andrew Pavia, Michael Proschan, Grant Schulert, Nitin Seam, Virginia Sheikh, Steven Simpson, Kanal Singh, Susan Swindells, Phyllis Tien, Timothy Uyeki, Alpana Waghmare, Cameron Wolfe, Jinoos Yazdany, and Judith Aberg.
• Weill Cornell Medicine, New York, New York (R.M.G.).
• Ann. Intern. Med. 2024 Nov 1; 177 (11): 154715571547-1557.

DescriptionIn March 2020, the White House Coronavirus Task Force determined that clinicians in the United States needed expert treatment guidelines to optimally manage patients with COVID-19, a potentially life-threatening disease caused by a new pathogen for which no specific treatments were known to be effective.MethodsThe U.S. Department of Health and Human Services requested that the National Institutes of Health (NIH) take the lead in expeditiously convening a panel of experts to create "living" guidelines that would be widely accessible and capable of frequent updating as important new information became available.RecommendationsThe purpose of this article is to expand on the experiences of the NIH COVID-19 Treatment Guidelines Panel (the Panel) over the past 4 years, summarize the Panel's final recommendations for COVID-19, highlight some challenges and unanswered questions about COVID-19 management, and inform future responses to public health emergencies. The Panel was formed in March 2020, and the first iteration of the guidelines was released in April 2020. Now that the public health emergency has ended, the NIH COVID-19 Treatment Guidelines have sunsetted. This role will now fall to professional societies and organizations, such as the American College of Physicians, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the World Health Organization, all of which have been active in this area.

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