• Wencai Wang, Menghao Liu, Zun Wang, Luyao Ma, Yongqiang Zhao, Wei Ye, and Xianfeng Li.
• The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
• World Neurosurg. 2024 Oct 21.

BackgroundHydrocephalus ranks among the most prevalent neurosurgical conditions worldwide, with a growing body of literature suggesting a potential association with inflammation. Employing bibliometric methods, this research visually analyzes the scholarly output on inflammation in hydrocephalus over the past 2 decades and provides a scientific framework for delineating research pathways and addressing key issues in this field.MethodsPublications sourced from the Web of Science Core Collection as of July 18, 2024 encompassed articles and reviews in English spanning from January 1, 2000, to December 31, 2024. Statistical analyses of countries, institutions, authors, references, and keywords were conducted utilizing VOSviewer1.6.20 and CiteSpace6.3. R1.ResultsA total of 424 reviews and articles were included in the analysis, showcasing a rising trajectory in publications concerning inflammation and hydrocephalus over time. The United States emerged as the leading contributor in terms of publication output, with Harvard Medical School topping the list of institutions. Notably, World Neurosurgery and Journal of Neurosurgery emerged as the most prolific journals and the most frequently cited, respectively. Authors Keep, Richard F., and Xi, Guo Hua, demonstrated the highest productivity, while Karimy, J.K., emerged as the author with the highest co-citation count. Following thorough analysis, the predominant keywords identified include mechanisms, management, inflammation, posthemorrhagic hydrocephalus, cerebrospinal fluid, surgery, microglia, risk factors, and choroid plexus, reflecting current research hotspots likely to persist.ConclusionsThis study will help researchers determine the mainstream research directions and latest hotspots of inflammation in hydrocephalus and provide a reference for revealing the molecular mechanism of hydrocephalus.Copyright © 2024 Elsevier Inc. All rights reserved.

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