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- Masayoshi Yamasaki, Akira Taniguchi, Hirohito Minami, Tomoko Tada, Tadashi Yabana, and Yutaka Naito.
- Department of Neurology, Japanese Red Cross Ise Hospital, Japan.
- Intern. Med. 2024 Oct 4.
AbstractA 54-year-old woman with persistent fatigue and a high fever presented with central pontine myelinolysis (CPM) on brain imaging, despite the absence of neurological symptoms. The patient had a slightly low serum sodium concentration. Further investigation led to a diagnosis of primary splenic diffuse large B-cell lymphoma (PS-DLBCL). Brainstem auditory-evoked potentials (BAEP) indicated minor abnormalities. CPM was successfully resolved after splenectomy and immunochemotherapy. This is the first reported case of CPM in a patient with PS-DLBCL confirmed by a pathological diagnosis following splenectomy and BAEP-detected abnormalities that improved with immunochemotherapy.
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