• Ze Liang, Yi Ding, He Sui, Mei Wu, Yongmin Jin, and Weibo Wen.
• Department of Nuclear Medicine, Yanbian University Hospital, Yanji, China.
• Medicine (Baltimore). 2024 Sep 20; 103 (38): e39769e39769.

RationaleAdenoid cystic carcinoma is a rare malignant tumor of the salivary glands, with few reports of metastasis to the liver in the literature. We present a case where an isolated hepatic lesion of adenoid cystic carcinoma was identified using 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT).Patient ConcernsA 76-year-old male experienced abdominal pain and underwent an enhanced CT scan and magnetic resonance imaging, which revealed a liver mass. Subsequent 18F-FDG PET/CT identified hypermetabolic lesions in both the left and right lobes of the liver, suggesting malignancy, with no other abnormalities detected.DiagnosesA liver biopsy confirmed the diagnosis of adenoid cystic carcinoma.InterventionsNo intervention.OutcomesFollowing confirmation of the diagnosis, the patient chose to discontinue treatment and was discharged.LessonsHepatic metastasis from adenoid cystic carcinoma may be detected before the identification of the primary lesion. 18F-FDG PET/CT plays a critical role in differentiating benign from malignant liver tumors, selecting potential biopsy sites, and assessing the extent of metastatic disease.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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