• Minerva medica · Oct 2024

    Venous thromboembolism during pregnancy and postpartum period: an updated review.

    • Sanaullah Mojaddedi, Javairia Jamil, Andrew Abraham, Dawood Jamil, Hend Mansoor, and Islam Y Elgendy.
    • Graduate Medical Education, University of Central Florida College of Medicine, Orlando, FL, USA.
    • Minerva Med. 2024 Oct 11.

    AbstractVenous thromboembolism (VTE) is a leading cause of maternal mortality. The risk of VTE in pregnant and postpartum women is ~ five times higher compared with non-pregnant women. There is a physiological tendency to a hypercoagulable state, from conception to the postpartum period. Several non-obstetric risk factors independently increase the risk of VTE. Since most signs and symptoms of VTE might mimic those of a normal pregnancy, a high index of suspicion is warranted to establish the diagnosis. D-dimer, ultrasonography and computed tomography pulmonary angiography are the primary tools for VTE diagnosis. Management mainly revolves around systemic anticoagulation with heparin. Advanced therapy options exist, but these can be considered for selected high-risk cases.

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