• Bin SalleehHashim MHMFrom the Departments of Emergency Medicine and., Syed Amir Ahmad, Tahani Al Ahmadi, Uzma Y Kashif, Israa Y Bamogaddam, Lama H AlFakhri, and Abdullah F AlSaeed.
• From the Departments of Emergency Medicine and.
• Pediatr Emerg Care. 2024 Oct 15.

ObjectivesThe practice of administration of intravenous (IV) antimicrobial therapy in outpatient settings (OPAT) is a low-cost alternative to in-patient admission and treatment. There is, however, limited evidence supporting OPAT management protocols for children. The primary objective of this study was to describe the use of pediatric emergency-based OPAT, as well as the safety of this practice.MethodsThe study was a prospective, observational study conducted in pediatric emergency department of a tertiary care hospital. Children younger than 14 years who required pediatric emergency department-based OPAT were included in the study.ResultsThree hundred and ninety-two children were included in the study. The mean duration of OPAT was 3.5 days. Ceftriaxone was the most frequently used antimicrobial. Chest infection was the commonest indication, followed by sickle cell disease with fever and soft tissue infections. There were no major intravenous line-related complications over course of treatment. Most of the patients (89.5%) completed the OPAT course successfully. Only 10.4% patients required subsequent hospital admission, with failure to improve on the OPAT protocol being the main reason patients for admission. None of the admitted patients required intensive care settings or faced unexpected morbidity.ConclusionsOur results affirm that pediatric emergency-based OPAT is a safe yet effective practice in children with good clinical outcome. We believe that a reduction in admissions translates to better hospital resource utilization.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.

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