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Case Reports
Central retinal vein prethrombosis as an initial manifestation of protein S deficiency.
- Paulo de Tarso Ponte Pierre-Filho, Alessandra Maria Mont'Alverne Pierre, Maurício Abujamra Nascimento, and Ana Maria Marcondes.
- Department of Ophthalmology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil. paulopierre@hotmail.com
- Sao Paulo Med J. 2004 May 6; 122 (3): 134135134-5.
ContextRetinal vein thrombosis is most common in old people, and is often associated with systemic vascular disease. One of its rare systemic causes is protein S deficiency.Case ReportA case of a 21-year-old woman with retinal vein prethrombosis associated only with protein S deficiency is described. She presented with acutely reduced visual acuity and a central scotoma in her left eye. Warfarin therapy was initiated, and complete improvement in ophthalmoscopic findings was subsequently observed. This case illustrates that protein S deficiency is a factor that should be considered in cases of retinal vein occlusion, particularly in young patients.
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