• Sao Paulo Med J · Sep 2005

    Case Reports

    Cellular angiofibroma of the vulva: case report with clinicopathological and immunohistochemistry study.

    • Adilha Misson Rua Micheletti, Ana Cristina Araújo Lemos da Silva, Antonio Geraldo Nascimento, Cléber Sérgio Da Silva, MurtaEddie Fernando CandidoEF, and Sheila Jorge Adad.
    • Universidade Federal do Triângulo Mineiro, Uberaba, Minas Gerais, Brazil.
    • Sao Paulo Med J. 2005 Sep 1; 123 (5): 250252250-2.

    ContextCellular angiofibroma of the vulva is a rare tumor that was first described in 1997. It occurs in middle-aged women (average age: 47 years), has small size (< 3 cm) and well-circumscribed margins.Case ReportWe describe a case in a 51-year-old woman whose preoperative diagnosis was confounded with Bartholin's glandular cyst. The neoplasia was well delimited and made up of three characteristic components: fusiform cells forming small fascicles, numerous blood vessels and adipose tissue interspersed between the fusiform cells. The stroma cells were positive for vimentin and negative for CD34, protein S-100, actin and desmin. The differential diagnoses for this tumor include aggressive angiomyxoma, angiomyofibroblastoma, lipoma of fusiform cells, solitary fibrous tumor, perineurioma and leiomyoma.

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