• Sao Paulo Med J · Sep 2007

    Case Reports

    Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report.

    • Marcelo Lorenzi Marques, Gabriel Salum D'Alessandro, Daher Cezar Chade, Valéria Pereira Lanzoni, Samuel Saiovici, and Cláudio José Ramos de Almeida.
    • Hospital Professor Edmundo Vasconcelos, São Paulo, Brazil.
    • Sao Paulo Med J. 2007 Sep 6; 125 (5): 297299297-9.

    ContextPrimary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological patterns are even rarer and it is often difficult to morphologically distinguish them from metastatic colorectal adenocarcinoma.Case ReportWe present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient. Other primary sites for the tumor had been excluded and, in the absence of digestive tract tumor and for confirmation that it was a primary bladder tumor, an immunohistochemistry study was performed.

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