• Sao Paulo Med J · Jul 2000

    Prognosis related to staging systems for chronic lymphocytic leukemia.

    • J R de Faria, J S de Oliveira, R M Delbone de Faria, M R Silva, S Goihman, M Yamamoto, and J Kerbauy.
    • Division of Hematology, Universidade de Alfenas, Minas Gerais, Brazil.
    • Sao Paulo Med J. 2000 Jul 6; 118 (4): 838883-8.

    ContextChronic lymphocytic leukemia (CLL) is a clonal lymphoproliferative disorder, characterized by B lymphocytic proliferation. CLL is the most frequent adult leukemia in Western countries, accounting for 25 to 30% of all white leukemic patients.ObjectiveTo evaluate clinical and staging characteristics in prognosis of chronic lymphocytic leukemia.DesignEvaluation of clinical-staging data.SettingUniversidade Federal de São Paulo - Escola Paulista de Medicina / Universidade de Alfenas.Sample73 patients diagnosed from 1977 to 1994.Main MeasurementsSex, ethnic origin, age, lymphadenopathy, splenomegaly, hepatomegaly, three or more areas of lymphoid enlargement, hemoglobin (g/dl), lymphocytes/mm3, Platelets/mm3ResultsMean survival of patients was 76 months, median age was 65 years, ranging from 33 to 87. Forty-four patients (60.3%) were male and 29 (39.7%) female.ConclusionThe Binet system determined a better prognosis than Rai.

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