• Pak J Med Sci · Oct 2024

    Comparison between modified and conventional combined Trabeculotomy-Trabeculectomy with Mitomycin-C for intraocular pressure reduction in primary congenital glaucoma.

    • Ahmed Raza, Muhammad Ajmal Chaudhary, Asma Mushtaq, and Asad Aslam Khan.
    • Ahmed Raza, MBBS, FCPS, FPO Department of Pediatric Ophthalmology, The University of Child Health Sciences, Lahore, Pakistan.
    • Pak J Med Sci. 2024 Oct 1; 40 (9): 193719401937-1940.

    ObjectivesTo determine the efficacy of modified combined trabeculotomy-trabeculectomy (CTT) with mitomycin-C (MMC) versus conventional CTT with MMC for intraocular pressure (IOP) reduction in patients with primary congenital glaucoma (PCG).MethodsThis interventional study was carried out in The Institute of Ophthalmology, Lahore from January 2018 to June 2019. We included 70 patients of either gender, with the age range from birth to ten years and with PCG having IOP >30 mm Hg. These patients were divided in groups A and B with 35 patients in each group. Patients in Group-A underwent modified CTT with MMC and in Group-B conventional CTT with MMC was carried out.ResultsThe mean age of our patients was 15.17 ± 12.39 months. Regarding gender, 57 (81.4%) were males and 13 (18.6%) were females. Baseline mean IOP in Group-A was 32.49 ± 1.01 mm Hg whereas in Group-B mean IOP was 31.97 ± 1.04 mm Hg. After one month, the mean IOP was 27.60 ± 1.72 mm Hg in Group-A, whereas mean IOP was 27.40 ± 1.82 mmHg in Group-B. After three months, the mean IOP was 21.63 ± 1.09 mm Hg in Group-A, whereas 20.97 ± 1.12 mm Hg in Group-B. In Group-A efficacy was achieved in 14 (40%) patients whereas in Group-B efficacy was achieved in 25 (71.4%) patients.ConclusionOur study revealed that conventional CTT with MMC showed better efficacy than modified CTT with MMC for reduction of IOP in PCG.Copyright: © Pakistan Journal of Medical Sciences.

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