• Vicente Orellana-Westermeyer, Claudia Quiroz Palominos, and Laura Carreño Toro.
• Departamento de Dermatología, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
• Rev Med Chil. 2024 Apr 1; 152 (4): 514517514-517.

AbstractAcquired epidermodysplasia verruciformis is a rare condition, secondary to a state of acquired immunosuppression and is characterized by a susceptibility to infection by human papillomavirus of the beta genus, which carries an increased risk of developing non-melanoma skin cancer. We report the case of a 39-year-old woman receiving a kidney transplant, treated with prednisone and tacrolimus, who after starting immunosuppressive therapy developed papules and warty plaques in the inguinal region. A skin biopsy was performed that was consistent with epidermodysplasia verruciformis, so it was decided to adjust immunosuppressive therapy to everolimus, which achieved a reduction in lesions. There are only 13 other cases of acquired epidermodysplasia verruciformis in kidney transplant recipients; to our knowledge this is the first case reported in Chile.

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