• Luis Rojas, Inés Ceron, Esteban Araos-Baeriswyl, Rodrigo Olivares, Andrés Valenzuela, and Andrés Aizman.
• Departamento de Medicina Interna, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
• Rev Med Chil. 2024 Mar 1; 152 (3): 302313302-313.

BackgroundThe constant increase of factors associated with the presence of resistant strains, makes empirical antibiotic selection a challenge in patients hospitalized for community-acquired urinary tract infection.AimWe characterized the bacteria and their antimicrobial susceptibility pattern in cultures obtained from adult patients that needed hospitalization for this disease in two tertiary hospitals in Santiago, Chile.MethodsWe conducted a prospective cross-sectional study in adults hospitalized for community-acquired urinary tract infection between 2017 and 2022. All patients with positive urine cultures were included in the analysis.ResultsA total of 830 patients were included. Escherichia coli was the most frequent infectious agent (68.1%), followed by Klebsiella spp. (17.7%) and Enterococcus faecalis (6.7%). Among Enterobacteriaceae strains, 35.2%, 19.7% and 27.2% were resistant to first, second and third-generation cephalosporin, respectively. 36.9% were resistant to ciprofloxacin and 1.8% to amikacin. Gram-positive bacteria were resistant to oxacillin and ampicillin in 25% and 18%, respectively.ConclusionWe detected a high prevalence of community-acquired urinary tract infections caused by bacteria resistant to commonly used antibiotics in adult patients that need to be hospitalized.

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