• Internal medicine · Oct 2024

    Management of Concurrent Immune Thrombocytopenia and Ulcerative Colitis: A Case Report and Literature Review.

    • Masataka Hirai, Minako Mori, Tomomi Sakai, Tomomi Oka, Yasuhiro Watanabe, Masaki Murata, Koki Moriyoshi, and Hiroshi Kawabata.
    • Department of Hematology, NHO Kyoto Medical Center, Japan.
    • Intern. Med. 2024 Oct 25.

    AbstractWe herein report a case of concurrent immune thrombocytopenia (ITP) and ulcerative colitis (UC) that achieved remission following mesalazine treatment. A 16-year-old girl presented with severe thrombocytopenia, abdominal pain, and bloody stool. She was initially diagnosed with ITP and then was treated with prednisolone, resulting in an immediate improvement of symptoms. Upon tapering the steroids, the symptoms recurred, thus leading to a subsequent diagnosis of UC via colonoscopy. Treatment with mesalazine promptly induced the remission of both ITP and UC, which was sustained. We reviewed 24 previously documented cases in which the simultaneous flares of UC and ITP were successfully managed.

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