• Francesco Salis, Maristella Belfiori, Michela Figorilli, Martina Mulas, Monica Puligheddu, and Antonella Mandas.
• Department of Medical Sciences and Public Health, University of Cagliari, 09042 Monserrato, Italy.
• Medicina (Kaunas). 2024 Oct 9; 60 (10).

AbstractBackground and Objectives: Sex differences are unclear in geriatric sleep medicine, and most evidence comes from inference from preclinical bases or clinical studies conducted on younger people. The aim of this study is to explore sex differences in sleep quality and daytime sleepiness in a cohort of elderly people. Materials and Methods: This cross-sectional study involved subjects aged 65 years or older undergoing multidimensional evaluation, including sleep quality and daytime sleepiness assessment with validated tools. Results: This study included 226 subjects (69.5% women), the majority of whom showed poor sleep quality (64.2%). A logistic regression model put one before the other sleep quality and gender. It initially showed that men were about half likely as women to have poor sleep quality (OR 0.48, 95%CI 0.27-0.86). Nonetheless, after adjusting for cognitive status and mood, the difference became smaller and insignificant (OR 0.72, 95%CI 0.38-1.38). Conclusions: Sex differences in elderly people's sleep quality seem to not be independent, appearing to be affected by alterations in cognitive status and mood.

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