• Daniel Perejón López, Laura Gascó Serna, María Catalina Serna Arnáiz, Miriam Orós Ruiz, Júlia Siscart Viladegut, Joaquim Sol, and Blanca Salinas-Roca.
• Department of Medicine, University of Lleida, Lleida, 25002, Spain.
• Fam Pract. 2024 Oct 21.

ObjectiveTo determine what effect maternal antenatal depression has on pregnancy and infant outcomes in the Lleida health region.MethodsRetrospective observational cohort study in pregnant women between 2012 and 2018 in the Lleida health region. Variables included age, body mass index, caesarean section, pre-eclampsia, birth weight, and Apgar score. We performed multivariate analysis, with linear regression coefficients and 95% confidence interval (CI).ResultsAntenatal depression was diagnosed in 2.54% pregnant women from a total sample of 17 177. Depression is significantly associated with a higher risk pregnancy and low birth weight. Pre-eclampsia, 1-minute Apgar score, and caesarean section were not significantly associated with depression.ConclusionsAntenatal depression increases the risk of pregnancy complications. In addition, depression in the mother increases the probability of low birth weight.© The Author(s) 2024. Published by Oxford University Press. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.

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