• Internal medicine journal · Nov 2024

    Injecting drug use is a risk factor for methicillin resistance in patients with Staphylococcus aureus bloodstream infections.

    • Stephanie J Curtis, Timothy Marvelianto Tedjo, Sue J Lee, Philip J Rawson-Harris, Kirsty Sim, Lucy O Attwood, JenneyAdam W JAWJDepartment of Infectious Diseases, The Alfred Hospital and School of Translational Medicine, Monash University, Melbourne, Victoria, Australia.Microbiology Unit, The Alfred Hospital, Melbourne, Victoria, Australia., and Andrew J Stewardson.
    • Department of Infectious Diseases, The Alfred Hospital and School of Translational Medicine, Monash University, Melbourne, Victoria, Australia.
    • Intern Med J. 2024 Nov 1; 54 (11): 190319081903-1908.

    AbstractWe investigated whether injecting drug use was a risk factor for methicillin resistance among inpatients with Staphylococcus aureus bloodstream infections (SABSIs) at an Australian health service. In 273 inpatients, 46 (16.9%) of SABSIs were methicillin-resistant S. aureus (MRSA). MRSA was more frequent in those who had injected drugs in the past 6 months (20.6%) compared with other inpatients (15.7%). Injecting drug use was associated with a 4.82-fold (95% confidence interval = 1.54-16.29) increased odds of MRSA after accounting for confounders.© 2024 Royal Australasian College of Physicians.

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