• Anesthesiology · Feb 2025

    Four-factor Prothrombin Complex Concentrate Use for Bleeding Management in Adult Trauma.

    • Lidia Mora, Marc Maegele, Oliver Grottke, Andreas Koster, Philipp Stein, Jerrold H Levy, and Gabor Erdoes.
    • Department of Anesthesiology, Intensive Care and Pain Clinic, Vall d'Hebron Trauma, Rehabilitation and Burns Hospital, Autonomous University of Barcelona, Barcelona, Spain.
    • Anesthesiology. 2025 Feb 1; 142 (2): 351363351-363.

    AbstractThe clinical use of four-factor prothrombin complex concentrate in adult trauma patients at risk of bleeding is supported by evidence for urgent reversal of oral anticoagulants but is controversial in acquired traumatic coagulopathy.

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