• Internal medicine · Nov 2024

    A Case of Superficial Esophageal Neuroendocrine Carcinoma with Marked Morphological Changes in a Short Period.

    • Mizuki Tanabe, Masahiro Saito, Kaname Uno, Tomoyuki Koike, Chiaki Sato, Waku Hatta, Naoki Asano, Fumiyoshi Fujishima, Takashi Kamei, and Atsushi Masamune.
    • Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
    • Intern. Med. 2024 Nov 1.

    AbstractA de novo whitish subepithelial lesion (SEL) with irregular vascular hyperplasia was detected in the lower thoracic esophagus during endoscopic surveillance. Special types of esophageal cancer were suspected; however, endoscopic biopsy specimens were inadequate for a diagnosis. Ten days later, endoscopic ultrasound showed a 7-mm homogeneously hypoechoic round mass in the submucosa, and a biopsy confirmed a histological diagnosis of esophageal neuroendocrine carcinoma (eNEC). Based on the clinical diagnosis of cT2N0M0, subtotal esophagectomy followed by adjuvant chemotherapy was performed immediately after endoscopic reexamination revealing a 20-mm reddish SMT. We herein report the marked changes in endoscopic findings of eNEC within 1.5 months.

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