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J Pain Symptom Manage · Nov 2024
Hypothalamic Hyperphagia in the Hospice Patient: Case Report and Discussion.
- Paul Joseph, Joseph Dixon, and Adam Marks.
- Division of Geriatric & Palliative Medicine (P.J., J.D., A.M.), University of Michigan, Ann Arbor, Michigan, USA. Electronic address: Parijog@gmail.com.
- J Pain Symptom Manage. 2024 Nov 2.
AbstractWe present a case of insatiable appetite and harmful overeating in a hospice patient that showcases the burden of hypothalamic hyperphagia, a rare complication of brain cancer. While confounders exist such as progression of disease and prior tapering of dexamethasone, in this case the initiation of metformin was associated with substantial appetite reduction and resolution of our patient's debilitating food-seeking behaviors. We will explore metformin as a potential cost-effective option for palliation in a hospice setting and explore some of the physiologic mechanisms involved.Copyright © 2024 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.
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