• Juan Chen, Yong Sun, Jian Luo, Yang Wu, Kaiyu Wang, Weiwen Zhang, and Honglong Fang.
• Department of Clinical Laboratory, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, Zhejiang, China.
• Medicine (Baltimore). 2024 Nov 8; 103 (45): e39808e39808.

RationalePsittacosis, also known as parrot fever, is an infectious disease caused by Chlamydia psittaci, which can lead to C psittaci pneumonia. Clinical manifestations are highly nonspecific, which can vary from asymptomatic infection to severe pneumonia and even death.Patient ConcernsIn this case presentation, we reported one 65-year-old male case of C psittaci pneumonia who was admitted to our hospital on December 2, 2022 due to the chief complaints of poor appetite and fatigue for 3 days as the clinical manifestations. He denied contact with birds but admitted riding horses 1 week ago.DiagnosesChlamydia psittaci pneumonia of patient was confirmed through metagenomic sequencing of bronchoalveolar lavage fluid under bronchoscopy.InterventionPatient was treated with V-V ECMO, invasive mechanical ventilation and CRRT.OutcomesOn December 12, the patient was successfully weaned off V-V ECMO and discharged on December 20, 2022. During postoperative follow-up, CT scan in a local hospital revealed the infiltrative lesions of the lung were absent.LessonsThis case prompts that metagenomic next-generation sequencing is a feasible diagnostic tool for psittacosis, which can rapidly worsen and even cause sudden cardiac arrest. V-V ECMO might be a viable emergency therapeutic option.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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