• Xiao Lin, Yizhou Fu, Richu Lin, Xiaqin Cai, and Mingli Zhang.
• Department of Ultrasound, Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
• Medicine (Baltimore). 2024 Nov 8; 103 (45): e40446e40446.

RationaleHorn pregnancy is a rare subtype of ectopic pregnancy that presents a diagnosis and treatment challenge due to its nonspecific symptoms and high risk of rupture.Patient ConcernsA 32-year-old woman without vaginal pregnancy with history of right corner who presented with painless vaginal bleeding.DiagnosesA transvaginal ultrasound revealed a pregnancy sac implanted in the left corner of the uterus, confirming the diagnosis of a cornual pregnancy.InterventionsTreatment options include pharmacological or surgical interventions, and anticipatory treatment is rarely recommended. Conservative treatment was chosen after extensive consultation, and the patient was treated with low molecular weight heparin and traditional Chinese medicine.OutcomesSubsequent ultrasound tests showed stable fetal development and a successful cesarean section.LessonsThis case highlights the success of combining low molecular weight heparin with traditional Chinese medicine in the treatment of cornual pregnancy. Factors affecting horn pregnancy, diagnostic challenges, and treatment considerations are discussed. Further research is necessary to determine the best management strategy and to ensure safe delivery for patients with impaired fertility but a strong desire to conceive.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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