• Medicine · Nov 2024

    Current status and prospects of congenital adrenal hyperplasia: A bibliometric and visualization study.

    • Sheng Chen, Lingling Wu, Xiaohan Ma, Lin Guo, Jianqiang Zhang, Hongjun Gao, and Ting Zhang.
    • Graduate School, Guangxi University of Chinese Medicine, Nanning, Guangxi, China.
    • Medicine (Baltimore). 2024 Nov 8; 103 (45): e40297e40297.

    BackgroundCongenital adrenal hyperplasia (CAH) is increasingly prevalent, leading to a surge in related research. To pinpoint emerging trends and recommend future directions, a bibliometric analysis of relevant CAH literature was performed.MethodsFrom January 1, 2000, to October 1, 2023, we searched the Web of Science Core Collection for CAH literature. For the bibliometric analysis, tools such as VOSviewer, CiteSpace, and the R package "bibliometrix" were employed.ResultsThe United States and England are at the forefront among 113 countries, contributing 5034 papers to CAH research. However, there is a need for more extensive global collaboration across institutions in this field. The number of publications on CAH is increasing annually. Leading research institutions include the University of Michigan, University of California, San Francisco, Karolinska Institutet, and Karolinska University Hospital. The Journal of Clinical Endocrinology & Metabolism is the most cited in this area. The most prolific author is Falhammar H, with 88 publications, 2568 co-citations, and a significant overall contribution. Key research areas include diagnostic methods and therapeutic strategies for CAH. Emerging research hotspots are identified by keywords such as "disorders of sex development," "21-hydroxylase deficiency," "ambiguous genitalia," "testosterone" and "adrenal insufficiency."ConclusionsResearch on CAH is expected to expand globally. Future studies will primarily focus on exploring CAH's diagnostic aspects and developing new therapies. This paper will help scholars better understand the dynamic evolution of the CAH and point out the direction for future research.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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