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Review
Deciphering the role of LncRNA in alcoholic liver disease: Mechanisms and therapeutic potential.
- Lin Zhang, Rongqi Wang, Yuemin Nan, and Lingbo Kong.
- Department of Traditional and Western Medical Hepatology, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
- Medicine (Baltimore). 2024 Nov 8; 103 (45): e40378e40378.
AbstractAlcoholic liver disease (ALD) is a spectrum of liver damage caused by chronic alcohol consumption. The disease progresses in stages, starting with simple fatty liver, progressing to alcoholic hepatitis and potentially leading to fibrosis and cirrhosis. The pathophysiology of ALD is complex and involves several cellular and molecular mechanisms. Recent research has highlighted the role of long non-coding RNAs (LncRNAs) as critical regulators in the development and progression of ALD. This article reviews the current understanding of LncRNAs in ALD, focusing on their functions in key pathological processes and their potential as diagnostic markers and therapeutic targets.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.
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