• Annals of medicine · Dec 2024

    Meta Analysis

    Effect of different training modalities on lipid metabolism in patients with type ii diabetes mellitus: a network meta-analysis.

    • Shuangtao Xing, Yaming Xie, Yifan Zhang, Runze Zhang, Dan Zeng, and Xianfeng Yue.
    • School of Physical Education, Henan Normal University, Xinxiang, Henan, China.
    • Ann. Med. 2024 Dec 1; 56 (1): 24284322428432.

    Background/AimsThis study to evaluate the effects of different training modalities on blood lipids in type II diabetic patients by Network Meta-analysis, and provide a relevant basis for patients to develop exercise prescriptions to regulate blood lipids.MethodsRandomized controlled trials (RCTs) were retrieved from Zhiwang, Wanfang, Wipu, PubMed, EBSCO, Cochrane Library, and Web of Science that were published from the establishment to February 2023. Relevant statistical analyses were performed using Stata 17.0 software and Revman 5.4.ResultsA total of 35 randomized controlled trials with 2771 patients with type II diabetes were finally included. The results of Network Meta-analysis showed that, compared with the control group, Chinese traditional fitness exercise (CTF), resistance training (RT), and aerobic training (AT) could reduce total cholesterol (TC) levels; CTF, RT, whole body vibration training (WBV), and AT could reduce triacylglycerol (TG) levels; CTF, WBV and AT could increase High-density lipoprotein cholesterol (HDL) levels; CTF, RT and AT could reduce Low-density lipoprotein cholesterol (LDL) levels. SUCRA probability ranking results showed that CTF was the most effective in reducing TC[SMD= -0.57, 95% CI (-0.83, -0.31), p < 0.001], TG[SMD= -0.24, 95% CI (-0.36, -0.12), p < 0.001], LDL[SMD= -0.52, 95% CI (-0.70, -0.35), p < 0.001]; RT was the most effective in increasing HDL[SMD = 0.14, 95% CI (0.03, 0.26), p < 0.05].ConclusionsCTF is more effective in improving TC, TG and LDL levels, while RT is most effective in improving HDL levels.

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