• Critical care clinics · Jan 2025

    Review

    Pediatric Post-Intensive Care Syndrome and Current Therapeutic Options.

    • Cydni N Williams, Neethi P Pinto, and Gillian A Colville.
    • Division of Pediatric Critical Care, Department of Pediatrics, Pediatric Critical Care and Neurotrauma Recovery Program, 707 SW Gaines Street, CDRC-P, Portland, OR 97239, USA. Electronic address: willicyd@ohsu.edu.
    • Crit Care Clin. 2025 Jan 1; 41 (1): 537153-71.

    AbstractPost-intensive care syndrome (PICS) impacts most pediatric critical care survivors. PICS spans physical, cognitive, emotional, and social health domains and is increasingly recognized in survivorship literature. Children pose unique challenges in identifying and treating PICS given the inherent population heterogeneity in pediatric samples with biological differences across ages and neurodevelopmental stages, unique disease pathophysiology, strong environmental influences on disease and recovery, and lack of standardized measurements to identify morbidities or track response to intervention. Emerging literature and the recent development of specialized multidisciplinary clinics highlight opportunities for intervention across PICS domains in inpatient and outpatient settings.Copyright © 2024 Elsevier Inc. All rights reserved.

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