• Hai-Jiang Yu, Lin Han, Wei-Feng Wang, Lin-Hong Yang, and Yu-Fei Nie.
• Department of Otorhinolaryngology, First Affiliated Hospital of Jiamusi University.
• Medicine (Baltimore). 2019 Jul 1; 98 (30): e16632e16632.

BackgroundThis study aims to systematically explore the efficacy and safety of mometasone furoate (MTF) for patients with nasal polyps (NP).MethodsWe will search MEDLINE, Cochrane Library, PubMed, Springer, Web of Science, Ovid, Wangfang and Chinese Biomedical Literature Database from their inception to April 30, 2019 without language restrictions. All randomized controlled trials (RCTs) of MTF for the treatment of NP will be considered for inclusion. RevMan 5.3 software will be used for data synthesis, subgroup analysis, sensitivity analysis, as well as the meta-analysis.ResultsPrimary outcomes include change in symptom scores (as measured by any symptom scores), and polyp size (as assessed by any Polyp size scores or tools). Secondary outcomes consist of polyp recurrence, change in nasal air flow, quality of life outcomes (as measured by any quality of life scales, such as Short Form Health Survey is a 36-item), and adverse events.ConclusionThis study will provide evidence for judging whether MTF is an effective and safe treatment for NP or not.Prospero Registration NumberPROSPERO CRD42019134037.

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