• Çiğdem Yalçin, Mehmet Alper Salman, Suna Aşkin Turan, Güldane Karabakan, and Harun Özmen.
• Department of Algology, Mersin City Training and Research Hospital, Mersin, Türkiye.
• Medicine (Baltimore). 2024 Nov 15; 103 (46): e40504e40504.

AbstractThere is a paucity of research and evidence, regarding the effectiveness of applying bipolar pulsed radiofrequency (bPRF) in osteoarthritis of the knee. This study aimed to search for the impact of intra-articular bPRF (IA-bPRF) on pain, functionality, and quality of life in individuals with advanced knee osteoarthritis. A total of 35 patients experiencing knee pain were included in the study. IA-bPRF was applied at 42 °C temperature, 45 V, with a pulse-width of 20 ms and a frequency of 2 Hz for 3 cycles of 120 seconds. Pain severity was evaluated using the numeric rating scale. Assessment tools included Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Lequesne Algofunctional Index for knee. All measurements were made before the intervention, as well as 2 weeks and 6 months after application of IA-bPRF. Significant improvement was observed in numeric rating scale scores for walking pain from 8.57 ± 0.17 to 4.11 ± 0.35, total WOMAC scores decreased from 75.5 ± 2.71 to 36.7 ± 3.6 and Lequesne Algofunctional Index for knee scores decreased from 18.6 ± 0.70 to 10.4 ± 0.93 by the end of the sixth month (P < .01). WOMAC subgroups for pain, stiffness and functionality, were also significantly lower at the 2nd week and 6th month compared to pre-intervention scores (P < .01). No serious adverse events related to the procedure occurred. IA-bPRF use seems to be safe and effective in relieving pain among individuals with advanced knee osteoarthritis. As a result, with further research, we expect that IA-bPRF may be considered for inclusion in upcoming guidelines for the treatment of chronic pain related to osteoarthritis of the knee.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

21 keywords...

hide…