• Qiuping Ning, Zheng Zhang, Hua Ren, Tiebing Fan, and Chunzhi Li.
• Qiuping Ning, Department of Radiology, Kulun Banner Mongolian Medicine Hospital, Tongliao City, Inner Mongolia 028200, China. Department of Radiology, China Academy of Chinese Medical Sciences, Xiyuan Hospital, Beijing 100091, China.
• Pak J Med Sci. 2024 Nov 1; 40 (10): 241024152410-2415.

ObjectivesUsing magnetic resonance imaging (MRI), we analysed the clinical manifestations of granulomatous lobular mastitis (GLM) before and after treatment with traditional Chinese medicine (TCM).MethodsThis was a retrospective study. Clinical manifestations and imaging features of patients with biopsy-proven GLM before and after treatment were retrospectively analysed from April 2021 to April 2023 at Xiyuan Hospital, China Academy of Chinese Medical Sciences.ResultsAmong 29 women of childbearing age (mean age, 34.3±3.6 years), Compared to pre-therapy, the number of patients with lumps, ruptures, pain, and menstrual irregularities was significantly reduced (P < 0.05). The Chinese medicine staging demonstrated a transition from bulk to ulcerated (P=0.041). Pre- and post-treatment MRI changes included lesion number, distribution, maximal diameter, time-signal intensity curves (TIC), apparent diffusion coefficients (ADC), and BI-RADS categories 3 and 4a (all P<0.05). Furthermore, substantial changes were seen in chest wall invasion, nipple discharge, increased feeding arteries, and skin edema (all P<0.05).ConclusionCombining internal and external Traditional Chinese Medicine (TCM) therapy proved successful for GLM. A reliable assessment of therapy efficacy is provided by MRI examination of lesion changes before and after treatment.Copyright: © Pakistan Journal of Medical Sciences.

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