• Xuebin Tang, Chengqiang Zhou, Hua Li, Liang Qiao, Yifeng Liao, Junwei Zhang, Yunqing Wang, and Lin Xie.
• Department of Orthopedics, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, Jiangsu, China; Department of Orthopedics, The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, Jiangsu, China.
• World Neurosurg. 2024 Nov 23.

ObjectiveTo investigate the effect of intravertebral cleft sclerosis on the efficacy of percutaneous vertebroplasty (PVP) in osteoporotic vertebral compression fractures (OVCF).MethodsWe analyzed 68 OVCF patients with intravertebral clefts treated with PVP from January 2020 to June 2022. Patients were divided into two groups based on CT findings: intravertebral clefts sclerosis (IVCs, 36 cases) and intravertebral clefts non-sclerosis (IVCns, 32 cases). Preoperative data included gender, age, bone mineral density, fractured vertebrae distribution, and disease duration. Excluding those with contraindications, all underwent PVP. Operation time, cement injection volume, leakage rate, and distribution patterns were recorded. Outcomes were evaluated using VAS scores, ODI, anterior vertebral height, and Cobb angle preoperatively, and at 2 days and 1 year postoperatively.ResultsThe IVCs group had a longer disease duration (P<0.05). No significant differences in operation time, cement volume, or leakage rate were observed between groups (P>0.05). Cement distribution was mass-like in IVCs and sponge-like in IVCns (P<0.05). Both groups showed significant improvements postoperatively (P<0.05), but IVCns had better recovery in anterior vertebral height, Cobb angle, and ODI (P<0.05).ConclusionIVCs affect cement distribution and recovery outcomes, with IVCns achieving better results. Early treatment is advised for OVCF with intravertebral clefts.Copyright © 2024. Published by Elsevier Inc.

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