• Gabi U Dachs, Margaret J Currie, Fiona McKenzie, Mona Jeffreys, Brian Cox, Sunia Foliaki, Loïc Le Marchand, and Bridget A Robinson.
• Angiogenesis Research Group, Department of Pathology, University of Otago, Christchurch, New Zealand.
• Lancet Oncol. 2008 May 1; 9 (5): 473484473-84.

AbstractPolynesia consists of several islands that are scattered across a vast triangle in the Pacific, and include New Zealand, Hawaii, and the Pacific islands. There are reported differences in the types of cancer and epidemiologies seen among communities in these islands, the reasons for which are diverse and complex. In this Review, we describe patterns of cancer incidence, mortality, and survival in indigenous populations compared with populations of European origin in Polynesia, and highlight the limited available data for Pacific populations. Additionally, we document the current knowledge of the underlying biology of cancers in these populations, and report risk factors that differ between ethnicities, including smoking, viral infections, and obesity. Disparities in measures of health are highlighted, as are evident differences in knowledge of tumour biology and cancer management between majority and minority populations.

48 keywords...

hide…