• Pain Med · Nov 2024

    A Mendelian randomization study finds no evidence for causal effects of C-reactive protein (CRP) on chronic pain conditions.

    • Pradeep Suri, Yakov A Tsepilov, Elizaveta E Elgaeva, WilliamsFrances M KFMKDepartment of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK., Maxim B Freidin, and Ian B Stanaway.
    • Division of Rehabilitation Care Services, VA Puget Sound Health Care System, USA.
    • Pain Med. 2024 Nov 26.

    AbstractThis two-sample Mendelian randomization study examined causal associations of C-reactive protein (CRP) with spinal pain, the extent of multisite chronic pain, and chronic widespread musculoskeletal pain. No causal associations were found between CRP and these pain conditions.© The Author(s) 2024. Published by Oxford University Press on behalf of the American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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