• Khadija Assis Pascholatto, Laura Ribeiro Santos, Thelma Larocca Skare, Odery Ramos Júnior, and Renato Nisihara.
• Mackenzie Evangelical School of Medicine of Paraná - Curitiba (PR), Brazil.
• Rev Assoc Med Bras (1992). 2024 Jan 1; 70 (12): e20240963e20240963.

BackgroundInflammatory bowel diseases such as Crohn's disease and ulcerative colitis are influenced by environmental and immunological factors and may differ according to the patient's sex.ObjectiveThe objective was to study the differences in the clinical profile of a Brazilian sample of inflammatory bowel disease patients according to sex.MethodsRetrospective study with chart review of 158 inflammatory bowel disease patients (43 with Crohn's disease and 115 with ulcerative colitis) from a single university hospital in southern Brazil.ResultsThe Crohn's disease sample showed a female/male ratio of 2.1, and the sample of ulcerative colitis showed a ratio of 1.5. The only significant difference found in the clinical profile was an increased constipation rate in female patients with ulcerative colitis. No other differences in epidemiological, symptom profile, or treatment could be detected.ConclusionsMore females with inflammatory bowel diseases sought healthcare facilities compared to males. The only notable difference was a higher incidence of constipation symptoms among females; all other aspects were similar between the sexes.

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