• Annals of medicine · Dec 2024

    Review

    Clinical features and progress in diagnosis and treatment of amyotrophic lateral sclerosis.

    • Dongxiang Yuan, Shishi Jiang, and Renshi Xu.
    • Department of Neurology, Jiangxi Provincial People's Hospital; The Clinical College of Nanchang Medical College; The First Affiliated Hospital of Nanchang Medical College; Xiangya Hospital of Center South University, Jiangxi Hospital; National Regional Center for Neurological Disease, Honggutan District, Nanchang, Jiangxi Province, China.
    • Ann. Med. 2024 Dec 1; 56 (1): 23999622399962.

    AbstractAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease of the central nervous system. Despite a large number of studies, the current prognosis of ALS is still not ideal. This article briefly describes the clinical features including epidemiology, genetic structure and clinical manifestations, as well as the progress of new diagnostic criteria and treatment of ALS. Meanwhile, we also discussed further both developments and improvements to enhance understanding and accelerating the introduction of the effective treatments of ALS.

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