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Case Reports
Hematopoietic cell transplantation for blood cancer patients living with HIV in Taiwan - A case series.
- Yi-Wei Lee, Eve Chen, Yi-Ting Chuang, Wei-Li Ma, and Shang-Ju Wu.
- Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
- J Formos Med Assoc. 2024 Dec 7.
AbstractPeople living with HIV (PLWH) have an increased risk of developing cancers, especially hematologic malignancies (HM). Hematopoietic stem cell transplantation (HSCT) has been an important treatment modality for patients with HM. However, the experience of HSCT in PLWH with HM remains limited in Asia. Therefore, we describe a case series of PLWH treated with HSCT in Taiwan. In these PLWH patients, HSCT procedures, either autologous (auto-HSCT) or allogeneic (allo-HSCT), were feasible with acute toxicity profiles comparable to those in non-HIV patients. However, auto-HSCT seemed unable to lead toward durable remission in PLWH with relapsed/refractory lymphoma, implicating that allo-HSCT might warrant early considerations for consolidation purposes in this distinct patient group.Copyright © 2024 Formosan Medical Association. Published by Elsevier B.V. All rights reserved.
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