• Ryan Comes, Cara Olsen, Chih Huang, Michael Carrillo, Seng Patton, Michael D April, Jennifer H Hall, Peter Kulis, and Andrew Hall.
• 81st Medical Group, Keesler AFB, MS 39534, USA.
• Mil Med. 2024 Dec 2.

IntroductionBlood is critical to expeditionary casualty care. Currently, low-titer O whole blood is the preferred product, because it serves as a universal blood product, but demand is higher than supply. Type-specific whole blood (TSWB) has the potential to address this shortfall and provide an identical clinical benefit to specific patient populations. This study estimates the benefit of TSWB to the expeditionary blood supply.Materials And MethodsPotential TSWB demand was estimated based on the product demand during the US involvement in Afghanistan (2001-2021). Potential production yield increases were based on blood production at the Keesler AFB Blood Distribution Center (FY2016-FY2023).ResultsIncluding type A TSWB is estimated to increase whole blood production 11.1% monthly. Type-specific whole blood, if available, is expected to be utilized in 20.7% to 35.6% of U.S. Military casualties requiring blood transfusion. Seasonality was found in production (P < .001).ConclusionsIncorporating TSWB is anticipated to meaningfully expand whole blood availability to meet current shortfalls and future expeditionary casualty needs.Published by Oxford University Press on behalf of the Association of Military Surgeons of the United States 2024. This work is written by (a) US Government employee(s) and is in the public domain in the US.

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