• Br J Surg · Nov 2024

    Global collaboration between platform trials in surgery and anaesthesia.

    • James Glasbey, Steve A Webb, Trisha Peel, Thomas D Pinkney, and Paul S Myles.
    • Academic Department of Surgery, University of Birmingham, Birmingham, UK.
    • Br J Surg. 2024 Nov 27; 111 (12).

    AbstractLarge, randomized trials are the bedrock of evidence-based medicine, but the resources required to complete such trials greatly limit the number of important clinical questions that can be addressed within a reasonable period of time. Adaptive platform trials can identify effective, ineffective, or harmful treatments faster. These trials have been shown to deliver rapid evidence through the COVID-19 pandemic and are now being adopted across surgery and anaesthesia, with many opportunities for surgeons, anaesthetists, and other perioperative physicians to conduct and collaborate in platform trials.© The Author(s) 2024 published by Oxford University Press on behalf of BJS Foundation Ltd and published by Elsevier Ltd on behalf of British Journal of Anaesthesia Society.

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