• Kfir Siag, Miki Paker, Salim Mazzawi, Yoni Evgeni Gutkovich, Moran Barcan, Shani Fisher, and Michael Ziv.
• Department of Otolaryngology-Head and Neck Surgery, Emek Medical Center, Afula, Israel.
• Isr Med Assoc J. 2024 Dec 1; 26 (11): 675681675-681.

BackgroundLittle is known about audiovestibular function in psoriasis, a chronic systemic inflammatory disease that affects 2% of the world's population.ObjectivesTo investigate audiovestibular function in patients with psoriasis.MethodsIn this prospective case-control trial, we enrolled 33 patients with psoriasis and 30 healthy controls. Audiologic testing included audiometry, tympanometry, and otoacoustic emissions recording. The vestibular investigation consisted of a dizziness handicap inventory questionnaire, a complete clinical vestibular examination, and video head impulse testing.ResultsThe psoriasis group showed significantly higher average hearing thresholds in both ears at all frequencies. Otoacoustic measurements differed significantly at 3000 Hz in the right (P = 0.026) and left ear (P = 0.034). The average dizziness handicap score was considerably higher in the psoriasis group, with a mean difference of 7.70 (P = 0.025). The number of patients with abnormal right anterior semicircular canal gain values was significantly higher in the psoriasis group (P = 0.047). Saccade analysis in the psoriasis group showed significantly higher number of patients with covert corrective saccades of the left posterior canal (P = 0.037) and significantly higher number of patients with abnormal interaural difference of corrective saccades in the plane of the right anterior-left posterior canals (P = 0.035).ConclusionsThe study demonstrates an association between psoriasis and audiovestibular impairment, which can affect quality of life. These results suggest that patients with psoriasis may be evaluated with audiometry for possible hearing loss. Vestibular testing may be pursued as clinically indicated.

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