• Resuscitation · Nov 2024

    Randomized Controlled Trial Multicenter Study

    Low physical activity level in out-of-hospital cardiac arrest survivors with obesity, mobility problems and cognitive impairment: Results from the TTM2 trial.

    • Katarina Heimburg, Blennow NordströmErikENeurology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden; Department of Rehabilitation Medicine, Skane University Hospital, Lund, Sweden., Josef Dankiewicz, Hans Friberg, Anders M Grejs, Matthias Hänggi, Thomas R Keeble, Hans Kirkegaard, Niklas Nielsen, Christian Rylander, Åsa B Tornberg, Susann Ullén, Matthew P Wise, Tobias Cronberg, and Gisela Lilja.
    • Neurology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden; Department of Cardiology, Skane University Hospital, Lund, Sweden. Electronic address: katarina.heimburg@med.lu.se.
    • Resuscitation. 2024 Nov 1; 204: 110407110407.

    AimsTo describe the level of physical activity 6 months after an out-of-hospital cardiac arrest (OHCA) and to explore potential risk factors of a low level of physical activity.MethodsPost-hoc analyses of the international multicentre Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac arrest (TTM2) trial. At 6 months, survivors at 61 sites in Europe, Australia and New Zeeland were invited to a follow-up. The participants answered two questions on self-reported physical activity. Answers were categorized as a low, moderate, or high level of physical activity and further dichotomized into a low versus moderate/high level of physical activity. Potential risk factors for a low level of physical activity were collected and investigated by univariable and multivariable logistic regression.ResultsAt 6 months, 807 of 939 (86%) OHCA survivors answered the two questions of physical activity; 34% reported a low, 44% moderate and 22% high level of physical activity. Obesity (OR = 1.75, 95% CI 1.10-2.77, p = 0.018), mobility problems by EuroQol 5 dimensions 5 levels (OR = 1.73, 95% CI 1.06-2.84, p = 0.029), and cognitive impairment by Symbol Digit Modalities Test (OR = 1.78, 95% CI 1.13-2.82, p = 0.013) were significantly associated with a low level of physical activity in the multivariable analysis.ConclusionOne third of the OHCA survivors reported a low level of physical activity. Obesity, mobility problems, and cognitive impairment were associated with a low level of physical activity.Gov IdentifierNCT02908308.Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.

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