• Raphael Romano Bruno, Bernhard Wernly, Antonio Artigas, Kristina Fuest, Stefan J Schaller, Lisa Dannenberg, Detlef Kindgen-Milles, Malte Kelm, Michael Beil, Sigal Sviri, Muhammed Elhadi, Michael Joannidis, Sandra Oeyen, Eumorfia Kondili, Rui Moreno, Susannah Leaver, Bertrand Guidet, Dylan W De Lange, Hans Flaatten, Wojciech Szczeklik, Christian Jung, and COVIP study group and collaborators on behalf of the COVIP study group. Electronic address: covip@med.uni-duesseldorf.de.
• Heinrich-Heine-University Duesseldorf, Medical Faculty, Department of Cardiology, Pulmonology and Vascular Medicine, Duesseldorf, Germany.
• J Crit Care. 2024 Dec 3; 86: 154984154984.

PurposeThere are limited data about the outcome of old intensive care (ICU) patients suffering from Covid-19 in the post-vaccination era. This study distinguishes the pre- and post-acute illness living conditions of ICU survivors from non-survivors.MethodsThis prospective international multicenter study included 642 old (≥ 70 years) ICU patients, including data ranging from pre-illness condition to functional 90-days follow-up. The primary endpoint was the difference of living conditions of ICU-survivors before ICU admission and 90-days after ICU discharge. Secondary outcomes were 90-days mortality, and quality of life.ResultsA total of 642 patients were included. Significantly more ICU survivors lived at their own homes without support before ICU admission than non-survivors (p = 0.016), while more non-survivors resided in nursing homes (p = 0.016). ICU mortality was 39 %, 30-days and 90 days mortality were 47 %and 55 %. After 90 days, only 22 % maintained the same living conditions. Surviving patients viewed ICU admission positively after 90 days, while relatives were more uncertain. Quality of life indicated a self-reported average score of 60 (50-75).ConclusionLiving conditions influence the outcome of critically ill old patients suffering from Covid-19. Only a minority returned to their initial habitat after ICU survival. Trial registration numberNCT04321265.Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.

4 keywords...

hide…