• Ramana K Naidu, Leonardo Kapural, Sean Li, Caitlin Tourjé, Joseph Rutledge, David Dickerson, and Timothy R Lubenow.
• MarinHealth Spine Institute, a UCSF Affiliate, 2 Bon Air Rd #120, Larkspur, CA, 94939, USA. ramonaidu@gmail.com.
• Curr Pain Headache Rep. 2025 Jan 13; 29 (1): 2525.

Purpose Of ReviewThe purpose of this review is to describe the development and key features of the Prospera™ Spinal Cord Stimulation (SCS) System, as well as the clinical evidence supporting its use. Prospera delivers therapy using a proprietary multiphase stimulation paradigm and is the first SCS system to offer proactive care through automatic, objective, daily, remote device monitoring and remote programming capabilities.Recent FindingsResults from the recently published BENEFIT-02 trial support the short-term safety and efficacy of multiphase stimulation in patients with chronic pain. BENEFIT-03 is an ongoing, multicenter, single-arm study with 24-month follow-up; interim analyses suggest that multiphase therapy is safe and effective and that patients and clinicians have positive experiences with remote device management. Preliminary evidence suggests that the Prospera SCS System represents an opportunity to improve patient care by combining an effective multiphase stimulation paradigm with an efficient proactive care model.© 2025. The Author(s).

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