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- Robert A Powell, Jessica S Coulter, and Ariel L Hoffman.
- From the Madigan Army Medical Center Family Medicine Residency, Tacoma, WA (RP, JC, AH).
- J Am Board Fam Med. 2025 Jan 17.
AbstractAt standard doses, direct oral anticoagulants (DOACs) were associated with a reduced risk of systemic embolism and intracranial hemorrhage (ICH) when compared with warfarin, with a greater derived benefit at lower creatinine clearance (CrCl-down to 25 mL/min). Lower doses of DOACs were associated with increased overall mortality without a significant decrease in ICH and incident bleeding when compared with standard dose DOACs and warfarin, across all CrCl down to 25 mL/min.1.© Copyright 2025 by Family Physicians Inquiries Network, Inc.
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